The Lyme Disease Network
Medical / Scientific Abstract

Title:Survival of Borrelia burgdorferi in antibiotically treated patients with Lyme borreliosis.
Authors:Preac-Mursic V, Weber K, Pfister HW, Wilske B, Gross B, Baumann A, Prokop J
Source:Infection 1989 Nov-Dec;17(6):355-9
Organization:Neurologische Klinik Grosshadern, M:unchen, FR Germany.

The persistence of Borrelia burgdorferi in patients treated with antibiotics is described. The diagnosis of Lyme disease is based on clinical symptoms, epidemiology and specific IgG and IgM antibody titers to B. burgdorferi in serum. Antibiotic therapy may abrogate the antibody response to the infection as shown in our patients. B. burgdorferi may persist as shown by positive culture in MKP-medium; patients may have subclinical or clinical disease without diagnostic antibody titers to B. burgdorferi. We conclude that early stage of the disease as well as chronic Lyme disease with persistence of B. burgdorferi after antibiotic therapy cannot be excluded when the serum is negative for antibodies against B. burgdorferi.

Adult, Antibiotics, IMMUNOLOGY, THERAPEUTIC USE, Borrelia burgdorferi, GROWTH & DEVELOPMENT, IMMUNOLOGY, ISOLATION &, PURIF, Case Report, Child, Preschool, Female, Human, Lyme Disease, DRUG THERAPY, IMMUNOLOGY, MICROBIOLOGY, Male, Middle Age, Recurrence

Language: Eng

Unique ID: 90129322

The Lyme Disease Network of NJ, Inc.
43 Winton Road
East Brunswick, NJ 08816