The Lyme Disease Network
Medical / Scientific Abstract


Title:Seronegative chronic relapsing neuroborreliosis.
Authors:Lawrence C, Lipton RB, Lowy FD, Coyle PK
Source:Eur Neurol 1995;35(2):113-7
Organization:Department of Medicine, Albert Einstein College of Medicine, New York, N.Y., USA.

Abstract:
We report an unusual patient with evidence of Borrelia burgdorferi infection who experienced repeated neurologic relapses despite aggressive antibiotic therapy. Each course of therapy was associated with a Jarisch-Herxheimer-like reaction. Although the patient never had detectable free antibodies to B. burgdorferi in serum or spinal fluid, the CSF was positive on multiple occasions for complexed anti-B. burgdorferi antibodies, B. burgdorferi nucleic acids and free antigen.

Keywords:
Antibiotics, ADVERSE EFFECTS, THERAPEUTIC USE, Antibodies, Bacterial, CEREBROSPINAL FLUID, Antigen-Antibody Reactions, Case Report, Chronic Disease, Female, Human, Lyme Disease, DRUG THERAPY, IMMUNOLOGY, Middle Age, Nervous System Diseases, DRUG THERAPY, IMMUNOLOGY, Recurrence

Language: Eng

Unique ID: 95317331


The Lyme Disease Network of NJ, Inc.
43 Winton Road
East Brunswick, NJ 08816
http://www.lymenet.org/